Insomnia often occurs in the context of co-morbid mental, physical, and sleep disorders. This Sleep DownUnder 2025 symposium showcases recent clinical trials of Cognitive Behavioural Therapy for insomnia (CBTi) and novel insomnia management approaches in diverse patient samples. Presenters explore the management of insomnia in the context of comorbid circadian rhythm disturbance, depression symptoms, sleep apnoea, and multi-morbidity. The session concludes with a presentation on the implementation of a stepped-care insomnia management model in Australia.